Inspiratory Muscle Training on Glycemic Control in Individuals With Type 2 Diabetes


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Primary Outcome Measures:
Secondary Outcome Measures:

  • Glucose in 8 weeks [ Time Frame: Evaluated in 8 weeks of inspiratory muscle training ]

    Fasting plasma glucose concentration after 8 weeks of inspiratory muscle training.

  • Glucose in 12 weeks [ Time Frame: Evaluated in 12 weeks of inspiratory muscle training ]

    Fasting plasma glucose concentration after 12 weeks of inspiratory muscle training.

  • Respiratory muscle strength in 8 weeks [ Time Frame: Evaluated in 8 weeks of inspiratory muscle training ]

    Maximum respiratory muscle strength after 8 weeks of inspiratory muscle training, through the measurement of the maximal inspiratory pressure (MIP) and maximal expiratory pressure (MEP).

  • Respiratory muscle strength in 12 weeks [ Time Frame: Evaluated in 12 weeks of inspiratory muscle training ]

    Maximum respiratory muscle strength after 12 weeks of inspiratory muscle training, through the measurement of the maximal inspiratory pressure (MIP) and maximal expiratory pressure (MEP).

  • Ventilatory muscle resistance [ Time Frame: Evaluated in 12 weeks of inspiratory muscle training ]

    Muscular endurance ventilatory after 12 weeks of inspiratory muscle training, through analysis of the MIP.

  • Lung functions [ Time Frame: Evaluated in 12 weeks of inspiratory muscle training ]

    Capacity and volumes lung after 12 weeks of inspiratory muscle training.

An acute high intensity inspiratory muscle exercise session was able to reduce glycemic levels (24%) similarly to an aerobic exercise session (25%) in subjects with type 2 diabetes, demonstrating that this type of exercise inspiratory muscle may have great potential in improving glycemic control.The present study will investigate if training of the inspiratory musculature for 8 and 12 weeks is capable of improving glycated hemoglobin, glucose and inspiratory muscle strength in individuals with type 2 diabetes. In addition, this study will evaluate the effect of inspiratory muscle training, with moderate loading of 30% of the MIP, on volumes and capacities lung in patients with type 2 diabetes. The subjects with type 2 diabetes will be recruited from the ambulatory of the Hospital de Clinicas de Porto Alegre and through newspaper advertisements.

Patients will be submitted to a general evaluation, including clinical history, physical examination, laboratory evaluation and application of the international physical activity questionnaire. Subsequently, individuals will perform assessments of lung functions (lung function assessment, ventilatory muscle strength test, inspiratory muscle strength test) and autonomic assessment (Ewing’s tests). Patients will be randomized to perform inspiratory muscle training with a placebo load (MIP 2%) or with moderate intensity (MIP 30%). Upon the randomization, participants will initiate inspiratory musculature training. The exams of HbA1c, glucose and ventilatory muscle strength tests will be performed in three moments: 1) at the initial assessment, 2) in the eighth week of inspiratory muscle training, and 3) at the end of the training (twelfth) week. During inspiratory muscle training, individuals will attend on Hospital de Clinicas de Porto Alegre, once a week, to the supervision of the way the exercise is being performed. Furthermore, it will be set to load on the PowerBreathe ® device for the following week.