Tooth Extraction in Patients With Atrial Fibrillation in Use of New Oral Anticoagulants


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Experimental: Rivaroxaban

As the rivaroxaban is ingested 1x/day, the interval between a maximum peak concentration and the other peak is 24 hours. Therefore, the surgery will be performed between two peaks of maximum drug concentration, knowing that the maximum peak concentration is an average of two hours after ingestion. So the surgical procedure should be scheduled 14 hours (2 hours+ 12 hours) after the last medication intake.

Drug: Rivaroxaban

Rivaroxaban 15 or 20mg tablet by mouth, every 24 hours, continuous use.

Other Name: Xarelto