Liposomal Bupivacaine Versus Standard Bupivacaine in the Adductor Canal for Total Knee Arthroplasty


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Experimental: Liposomal bupivacaine group

20ml 1.33% liposomal bupivacaine administered in adductor canal (a type of peripheral nerve block)

Drug: Peripheral Nerve Blockade

Each study arm will receive their respective formulation of local anesthetic, either standard bupivacaine or liposomal bupivacaine upon randomization

Behavioral: 10 meter walk test on post-operative day 1

Patient asked to walk 10 meters at comfortable pace on post-operative day one when deemed safe to do so by the physical therapist

Other: In person and over the phone questionnaire

Presuming the patient has left the hospital each patient will be called on post-operative day 2, 3 to assess nausea, opioid consumption, satisfaction with anesthesia technique, nausea and vomiting as well as pain scores

Device: Force transduction of quadriceps strength

Patient will be asked to flex quadriceps at maximal ability and a transducer (Kiio device) will record a force value pre operatively and on post operative day 1