SULTAN (Improving SUrgery of Liver Metastases: a Trial of the Arterial Chemotherapy Network)


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Drug: Oxaliplatin, Cetuximab, Bevacizumab, Panitumumab, Irinotecan, Leucovorin, 5Fluorouracil

Oxaliplatin 100mg/m² infusion in 2 hours, Cetuximab 500mg/m² infusion in 2 hours, Bevacizumab 5mg/kg infusion in 30 minutes, Panitumumab 6mg/kg, Irinotecan 180mg/m² over 90 minutes to begin 30 minutes after folinic acid infusion is started, Leucovorin 400mg/m² infusion in 2 hours, 5Fluorouracil 2400mg/m² infusion continuous in 46h